Prediction of Major Adverse Cardiovascular Events in Peripheral Artery Disease: Integrating Metabolomics and Proteomics for Risk Stratification
Wenxin Zhao, Lingbing Meng, Sheng Yan, Peng Li, Youjing Sun, Yaming Guo, Bowen Zhang, Yifan Cao, VIP-PADS Study Collaborators, Junhong Ren, Yongjun Li, Zuoguan Chen · 2026
Read Prediction of Major Adverse Cardiovascular Events in Peripheral Artery Disease: Integrating Metabolomics and Proteomics for Risk Stratification by Wenxin Zhao, Lingbing Meng, Sheng Yan, Peng Li, Youjing Sun, Yaming Guo, Bowen Zhang, Yifan Cao, VIP-PADS Study Collaborators, Junhong Ren, Yongjun Li, Zuoguan Chen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13148185.txt.
Description
Blocked leg arteries raise the odds of heart attacks and strokes, and Wenxin Zhao and a large team hunted blood markers that flag the riskiest patients. They studied 164 hospitalized patients set for a procedure to reopen their arteries. Blood proteins and small molecules were measured before follow-up.
Several proteins, including MMP3 and MMP19, ran high in patients who later suffered major events. A model built on the proteins sorted patients with strong accuracy. Molecule profiles pointed to changes in tryptophan and glycogen pathways. Protein-based scoring could help doctors watch the highest-risk patients more closely.
Catalog record
| CREATOR | Wenxin Zhao, Lingbing Meng, Sheng Yan, Peng Li, Youjing Sun, Yaming Guo, Bowen Zhang, Yifan Cao, VIP-PADS Study Collaborators, Junhong Ren, Yongjun Li, Zuoguan Chen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |