Impact of intraoperative nonsteroidal anti-inflammatory drugs on acute kidney injury after major noncardiac surgery: a propensity score-matched analysis
Cong Zhang, Yixin Liao, Xiaoyu Zhu, Wei Wang, Xinxin Liao · 2026
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Description
Cong Zhang and co-authors ask whether pain drugs given during major surgery raise the risk of kidney injury after it. Their 2026 study reviews records from one large teaching hospital. The drugs at issue are a common class used in mixed pain plans. Patients having planned non-heart surgery are split by whether they got the drugs during the operation. Matching pairs patients with like traits so the groups can be compared fairly.
More than eleven thousand patients enter the study, and matched pairs number over three thousand per side. Kidney injury rates land the same in both groups after matching. Injury severity and hospital stay length also match. Checks by drug type and by dose find no link either. A rerun on complete records gives the same answer. The authors read the drugs as safe for kidneys in this setting.
Catalog record
| CREATOR | Cong Zhang, Yixin Liao, Xiaoyu Zhu, Wei Wang, Xinxin Liao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |