Comparison of preoperative 5% povidone-iodine plus moxifloxacin versus 5% povidone-iodine alone on ocular surface bacterial flora: protocol for a randomized controlled trial

Mary Ogbenyi Ugalahi, Olufunmilola Bamidele Makanjuola, Steve Oluwaseun Adebusoye, Bolutife Ayokunnu Olusanya · 2026

Read Comparison of preoperative 5% povidone-iodine plus moxifloxacin versus 5% povidone-iodine alone on ocular surface bacterial flora: protocol for a randomized controlled trial by Mary Ogbenyi Ugalahi, Olufunmilola Bamidele Makanjuola, Steve Oluwaseun Adebusoye, Bolutife Ayokunnu Olusanya (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13147859.txt.

Description

Mary Ogbenyi Ugalahi and co-authors set out a trial protocol testing whether adding an antibiotic drop to the standard antiseptic improves germ control before cataract surgery. Infection inside the eye after surgery is rare but devastating, and it usually comes from the patient's own surface bacteria. The antiseptic povidone-iodine is standard everywhere, but the extra value of antibiotics is debated.

At a hospital in Ibadan, Nigeria, patients scheduled for cataract surgery will be randomized to antiseptic alone or antiseptic plus moxifloxacin drops. Swabs before and just before surgery will show how many eyes turn from culture-positive to negative. The trial also tracks remaining bacteria, species, and drug sensitivity to guide stewardship.

Catalog record

CREATORMary Ogbenyi Ugalahi, Olufunmilola Bamidele Makanjuola, Steve Oluwaseun Adebusoye, Bolutife Ayokunnu Olusanya
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13147859

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