ABSTRACT NUMBER: ESOC2026A1692 IS AGE A PROGNOSTIC OR PREDICTIVE FACTOR? A STUDY-LEVEL AND KAPLAN–MEIER–DERIVED INDIVIDUAL PATIENT DATA META-ANALYSIS OF PFO CLOSURE IN ADULTS AGED ≥60 YEARS
Ahmed Alkhiri, Fahad Alturki, Aser Alamri, Hassan Salamatullah, Faisal Almutawa, Shatha Alqurashi, Mohammed Alqahtani, Ashfaq Shuaib, Jeffrey Saver, Adel Alhazzani, Fahad Alajlan, Fawaz Alotaibi · 2026
Read ABSTRACT NUMBER: ESOC2026A1692 IS AGE A PROGNOSTIC OR PREDICTIVE FACTOR? A STUDY-LEVEL AND KAPLAN–MEIER–DERIVED INDIVIDUAL PATIENT DATA META-ANALYSIS OF PFO CLOSURE IN ADULTS AGED ≥60 YEARS by Ahmed Alkhiri, Fahad Alturki, Aser Alamri, Hassan Salamatullah, Faisal Almutawa, Shatha Alqurashi, Mohammed Alqahtani, Ashfaq Shuaib, Jeffrey Saver, Adel Alhazzani, Fahad Alajlan, Fawaz Alotaibi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13146837.txt.
Description
Ahmed Alkhiri and co-authors report a 2026 conference review on closing a small heart opening in stroke patients aged sixty and over. The opening is more common with age and may let clots cross to the brain. Trial proof for closing it in older adults, though, has been limited.
Fifteen studies with near twenty-eight thousand patients were pooled, using curves rebuilt into patient-level time data. Repeat stroke or warning events ran at about half the rate after closing versus drug care alone. Closing also cut repeat stroke over four years without raising the heart rhythm fault rate. Older patients still faced higher risks than younger ones overall. The authors read age as a risk marker, not a reason to withhold closing.
Catalog record
| CREATOR | Ahmed Alkhiri, Fahad Alturki, Aser Alamri, Hassan Salamatullah, Faisal Almutawa, Shatha Alqurashi, Mohammed Alqahtani, Ashfaq Shuaib, Jeffrey Saver, Adel Alhazzani, Fahad Alajlan, Fawaz Alotaibi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |