ABSTRACT NUMBER: ESOC2026A1903 GENETIC ASSOCIATION STUDY ON WHITE MATTER HYPERINTENSITY BURDEN IN SOUTH ASIANS USING WHOLE GENOME SEQUENCING DATA

M Janaki Nair, Aniket Mishra, Stephanie Debette · 2026

Read ABSTRACT NUMBER: ESOC2026A1903 GENETIC ASSOCIATION STUDY ON WHITE MATTER HYPERINTENSITY BURDEN IN SOUTH ASIANS USING WHOLE GENOME SEQUENCING DATA by M Janaki Nair, Aniket Mishra, Stephanie Debette (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13146746.txt.

Description

Janaki Nair, Aniket Mishra, and Stephanie Debette present this 2026 conference abstract on the genetics of brain white matter damage. Bright spots on brain scans mark small vessel disease and link to stroke and dementia. Most genetic work so far drew on European groups. The team studies South Asian people with whole-genome data.

They analyzed scans and genomes from 906 South Asian people in a large UK study. Of 27 known risk spots from European work, 15 showed the same direction of effect. No single hit reached the strict bar in this small group alone. Pooling with past data found two new risk spots. The authors stress the need for larger, mixed-ancestry studies.

Catalog record

CREATORM Janaki Nair, Aniket Mishra, Stephanie Debette
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13146746

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