ABSTRACT NUMBER: ESOC2026A741 META-ANALYSIS DETERMINING THE EFFECTIVENESS OF SOVATELTIDE TO TREAT ACUTE CEREBRAL ISCHEMIC STROKE
Amaresh Ranjan, Preyan Mehta, Anil Gulati · 2026
Read ABSTRACT NUMBER: ESOC2026A741 META-ANALYSIS DETERMINING THE EFFECTIVENESS OF SOVATELTIDE TO TREAT ACUTE CEREBRAL ISCHEMIC STROKE by Amaresh Ranjan, Preyan Mehta, Anil Gulati (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13146725.txt.
Description
Ranjan, Mehta, and Gulati (2026) pooled trial evidence on sovateltide, a drug marketed in India for acute ischemic stroke and now in late-stage trials abroad. Standard clot-dissolving drugs help some patients, and this analysis compared the newer drug's functional outcomes against both of them and against no clot treatment. Twenty-nine studies with 15,696 patients fed the comparison, using ninety-day disability scores.
Sovateltide beat alteplase on several outcome bands and matched or beat tenecteplase across them, with death and brain bleeding rates comparable throughout. Differences between studies were moderate, and bias checks looked clean. Two of the authors are employees and shareholders of the drug's maker, a conflict the abstract declares. The authors conclude the drug is effective and promising for acute stroke care.
Catalog record
| CREATOR | Amaresh Ranjan, Preyan Mehta, Anil Gulati |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |