ABSTRACT NUMBER: ESOC2026A1797 ORAL ANTICOAGULANTS FOR SECONDARY PREVENTION IN ATRIAL FIBRILLATION PATIENTS WITH PRIOR INTRACRANIAL HEMORRHAGE: A SYSTEMATIC REVIEW AND META-ANALYSIS OF TEN STUDIES
Mohamed Hamouda Elkasaby, Mohamed Sherif Ali Ahmed, Noha Elmahdi, Mahmoud Balata · 2026
Read ABSTRACT NUMBER: ESOC2026A1797 ORAL ANTICOAGULANTS FOR SECONDARY PREVENTION IN ATRIAL FIBRILLATION PATIENTS WITH PRIOR INTRACRANIAL HEMORRHAGE: A SYSTEMATIC REVIEW AND META-ANALYSIS OF TEN STUDIES by Mohamed Hamouda Elkasaby, Mohamed Sherif Ali Ahmed, Noha Elmahdi, Mahmoud Balata (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13146696.txt.
Description
A patient with atrial fibrillation who has already survived a brain bleed sits on a knife edge: blood thinners prevent strokes but may restart the bleeding. Mohamed Hamouda Elkasaby and three co-authors pooled the evidence in a meta-analysis of nine studies, three of them randomized trials. The analysis compared oral anticoagulants against no antithrombotic therapy in exactly this population.
In the trials, the drugs cut stroke risk substantially and ischemic events by nearly two thirds, but more than doubled hemorrhagic events. The observational studies agreed on fewer clots and lower overall mortality, with no clear rise in repeat brain bleeds. The authors conclude that restarting anticoagulants likely benefits carefully selected patients, and that the decision has to be weighed person by person rather than by rule.
Catalog record
| CREATOR | Mohamed Hamouda Elkasaby, Mohamed Sherif Ali Ahmed, Noha Elmahdi, Mahmoud Balata |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |