ABSTRACT NUMBER: ESOC2026A2062 WHITE MATTER MICROSTRUCTURAL DAMAGE IS ASSOCIATED WITH A PRO-INFLAMMATORY CIRCULATING IMMUNE CELL COMPOSITION IN CEREBRAL SMALL VESSEL DISEASE
Sanne van Winden, Oriane Marguet, Hao Li, Daniel J Tozer, Anil Tuladhar, Meritxell Nus, Ziad Mallat, Niels Riksen, Frank-Erik De Leeuw, Hugh Markus · 2026
Read ABSTRACT NUMBER: ESOC2026A2062 WHITE MATTER MICROSTRUCTURAL DAMAGE IS ASSOCIATED WITH A PRO-INFLAMMATORY CIRCULATING IMMUNE CELL COMPOSITION IN CEREBRAL SMALL VESSEL DISEASE by Sanne van Winden, Oriane Marguet, Hao Li, Daniel J Tozer, Anil Tuladhar, Meritxell Nus, Ziad Mallat, Niels Riksen, Frank-Erik De Leeuw, Hugh Markus (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13146675.txt.
Description
Sanne van Winden and nine co-authors link damage in the brain's white matter to the mix of immune cells in the blood. The setting is cerebral small vessel disease, a slow injury to tiny brain vessels that can harm thinking. Their 2026 conference abstract covers two hundred patients with symptoms who had MRI scans and blood draws. A diffusion measure scored fine damage in white matter that still looked normal. A cell-sorting method counted immune cell types in whole blood.
The team compared damage scores with the share of pro-inflammatory cells. A tie would suggest that body-wide inflammation walks with brain injury in this disease. That could open drug paths that calm the immune side. The abstract reports the design and the headline link named in its title.
Catalog record
| CREATOR | Sanne van Winden, Oriane Marguet, Hao Li, Daniel J Tozer, Anil Tuladhar, Meritxell Nus, Ziad Mallat, Niels Riksen, Frank-Erik De Leeuw, Hugh Markus |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |