ABSTRACT NUMBER: ESOC2026A440 SAFETY AND EFFICACY OF BOTULINUM TOXIN TYPE A FOR LOWER LIMB SPASTICITY IN POST-STROKE PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
Ibrahim Serag · 2026
Read ABSTRACT NUMBER: ESOC2026A440 SAFETY AND EFFICACY OF BOTULINUM TOXIN TYPE A FOR LOWER LIMB SPASTICITY IN POST-STROKE PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS by Ibrahim Serag (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13146269.txt.
Description
Ibrahim Serag presents this 2026 conference abstract pooling trials of botulinum toxin injections for stiff legs after stroke. Spasticity in the lower limb slows walking, raises fall risk, and shrinks independence for many survivors. Small trials of the toxin exist, but their combined verdict needed stating.
Following PRISMA rules, databases were searched for randomized trials comparing the toxin with placebo. Fourteen trials with 1,431 patients qualified. Pooled results favored the toxin: muscle tone fell by a mean difference of 0.55 points, and both Ashworth spasticity scales improved significantly. Subgroup checks at 4, 8, and 12 weeks explored how long benefits last. Risk of bias was scored with the Cochrane tool, and the analysis used a random-effects model.
Catalog record
| CREATOR | Ibrahim Serag |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |