ABSTRACT NUMBER: ESOC2026A1849 EARLY ANTIPLATELET THERAPY AFTER INTRAVENOUS THROMBOLYSIS FOR ACUTE ISCHEMIC STROKE: A COMPREHENSIVE META ANALYSIS WITH TRIAL SEQUENTIAL ANALYSIS

Hamdy A Makhlouf, Ahmed Harb, Moaz Abouelmagd, Anas Mansour, Ahmed Osman, Nada Mosad, Ahmed H Abdelaal, Omar Kassar, Jeffrey Saver · 2026

Read ABSTRACT NUMBER: ESOC2026A1849 EARLY ANTIPLATELET THERAPY AFTER INTRAVENOUS THROMBOLYSIS FOR ACUTE ISCHEMIC STROKE: A COMPREHENSIVE META ANALYSIS WITH TRIAL SEQUENTIAL ANALYSIS by Hamdy A Makhlouf, Ahmed Harb, Moaz Abouelmagd, Anas Mansour, Ahmed Osman, Nada Mosad, Ahmed H Abdelaal, Omar Kassar, Jeffrey Saver (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13146023.txt.

Description

Hamdy A Makhlouf and co-authors report a 2026 conference review on starting clot-preventing drugs within a day of clot-busting care for stroke. Early drugs might stop vessels from closing again and ward off early decline. They could also raise bleeding risk, and past trial results clash.

Twelve trials with more than forty-five hundred patients were pooled. Early drug care did not clearly improve function scores at any level. Odds of severe brain bleeding and death leaned higher with early care, though not past the bar for firm proof. One drug given by vein hinted at a function gain. The authors call the proof unsettled and ask for larger trials.

Catalog record

CREATORHamdy A Makhlouf, Ahmed Harb, Moaz Abouelmagd, Anas Mansour, Ahmed Osman, Nada Mosad, Ahmed H Abdelaal, Omar Kassar, Jeffrey Saver
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13146023

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