ABSTRACT NUMBER: ESOC2026A1910 PROCOAGULANT PLATELETS MEDIATE CEREBRAL ARTERIAL THROMBOSIS IN CANCER
Manuela De Michele, Paolo Amisano, Lucia Bertuccini, Francesca Spadaro, Paola Piscopo, Elisa Straface, Marta Iacobucci, Antonio Ciacciarelli, Angela Pascariello, Svetlana Lorenzano · 2026
Read ABSTRACT NUMBER: ESOC2026A1910 PROCOAGULANT PLATELETS MEDIATE CEREBRAL ARTERIAL THROMBOSIS IN CANCER by Manuela De Michele, Paolo Amisano, Lucia Bertuccini, Francesca Spadaro, Paola Piscopo, Elisa Straface, Marta Iacobucci, Antonio Ciacciarelli, Angela Pascariello, Svetlana Lorenzano (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13146001.txt.
Description
Manuela De Michele and nine co-authors wrote this 2026 conference study on how cancer helps cause strokes. Cancer patients clot too readily, and the mechanism behind clots in brain arteries was murky. The team compared eighty-five patients across three groups: cancer with stroke, stroke alone, and cancer alone, studying blood, retrieved clots, and platelet behavior.
The cancer-stroke patients' clots were built differently: rich in platelets and fibrin, laced with neutrophils and their sticky DNA traps, while ordinary stroke clots were mostly red cells. Their platelets leaned procoagulant and traveled with more platelet microparticles, and their plasma alone could push healthy donors' platelets into larger clumping aggregates. The authors name procoagulant platelets as central mediators of cancer-associated stroke, and as a target for prevention in a group whose strokes carry grim prognoses.
Catalog record
| CREATOR | Manuela De Michele, Paolo Amisano, Lucia Bertuccini, Francesca Spadaro, Paola Piscopo, Elisa Straface, Marta Iacobucci, Antonio Ciacciarelli, Angela Pascariello, Svetlana Lorenzano |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |