ABSTRACT NUMBER: ESOC2026A2374 ASSOCIATION OF ADMISSION UREA TO CREATININE RATIO TO THE MORTALTY IN HEMORRHAGIC STROKE: A SYSTEMATIC REVIEW AND META-ANALYSIS

Description

Sana Aftabi Yousefabad, Rasa Beheshti, Seyyed Sina Hejazian, Afshin Moaradi, Asal Ebrahimian, and Ramin Zand pool the evidence on whether a simple admission blood ratio predicts death after a bleeding stroke. The ratio divides blood urea nitrogen by creatinine, two routine lab values, and both reflect kidney function and hydration. The team searched three databases through July 2025 for studies of spontaneous brain hemorrhage that linked the ratio, measured within a week of arrival, to hospital or thirty-day death.

Five studies covering 89,415 patients qualified. Definitions of a high ratio varied, with cut-offs above fifteen or twenty in the largest studies. Pooling the adjusted results showed a modest but statistically firm association: higher ratios came with higher mortality, with an adjusted odds ratio of 1.02. The authors present the ratio as a readily available early warning marker, while noting the small size of the effect.

Catalog record

Source: https://europepmc.org/articles/PMC13145948