ABSTRACT NUMBER: ESOC2026A2027 DOUBLE-NEGATIVE T CELLS ATTENUATE POST-STROKE COGNITIVE IMPAIRMENT BY TARGETING MATURE B LYMPHOCYTES VIA THE NKG2D-RAE1 PATHWAY
Zhiyu Leng, Xiaoyi Jiang, Ming Yuan, Qinxue Sun, Yuhualei Pan, Gang Li · 2026
Read ABSTRACT NUMBER: ESOC2026A2027 DOUBLE-NEGATIVE T CELLS ATTENUATE POST-STROKE COGNITIVE IMPAIRMENT BY TARGETING MATURE B LYMPHOCYTES VIA THE NKG2D-RAE1 PATHWAY by Zhiyu Leng, Xiaoyi Jiang, Ming Yuan, Qinxue Sun, Yuhualei Pan, Gang Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13145849.txt.
Description
Zhiyu Leng and co-authors describe a 2026 conference lab study on memory loss after stroke and a type of immune cell that may ease it. The cells are called double-negative T cells. Earlier work by the group had shown that the cells can lessen stroke damage in mice.
In mice with stroke and low oxygen, the team found immune B cells entering the brain and leaving harmful deposits near memory areas. Giving the T cells improved memory test scores and brain cell signaling. The T cells slowed B cell growth and raised B cell death through a named cell pathway. The authors propose the cell transfer as a possible future treatment path.
Catalog record
| CREATOR | Zhiyu Leng, Xiaoyi Jiang, Ming Yuan, Qinxue Sun, Yuhualei Pan, Gang Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |