ABSTRACT NUMBER: ESOC2026A1642 LIMITED INCREMENTAL VALUE OF D-DIMERS COMBINED WITH GFAP FOR ACUTE STROKE SUBTYPE DIFFERENTIATION
Julien Paul, Florence Barrette, Catherine Brassard, Sarah-Emilie Godin, Ralph Nuhay, David Chiasson-Ricard, Laura Gioia · 2026
Read ABSTRACT NUMBER: ESOC2026A1642 LIMITED INCREMENTAL VALUE OF D-DIMERS COMBINED WITH GFAP FOR ACUTE STROKE SUBTYPE DIFFERENTIATION by Julien Paul, Florence Barrette, Catherine Brassard, Sarah-Emilie Godin, Ralph Nuhay, David Chiasson-Ricard, Laura Gioia (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13145844.txt.
Description
Julien Paul and six co-authors test whether adding a clotting marker to a brain protein test sharpens emergency stroke sorting. Their 2026 conference abstract uses a prospective cohort of 315 suspected stroke patients seen within a day of onset. The protein, GFAP, already separates brain bleeds from blocked-vessel strokes well.
GFAP ran far higher in hemorrhage, with discrimination of 0.87 and a best cutoff giving 69 percent sensitivity at 87 percent specificity. D-dimers ran higher in large-vessel blockages but discriminated weakly at 0.66. Among patients below the GFAP cutoff, adding D-dimers did not improve blockage detection at all. The authors conclude the second test adds little to the first. For triage teams, the abstract's message is restraint: one good marker beats a hopeful pair.
Catalog record
| CREATOR | Julien Paul, Florence Barrette, Catherine Brassard, Sarah-Emilie Godin, Ralph Nuhay, David Chiasson-Ricard, Laura Gioia |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |