ABSTRACT NUMBER: ESOC2026A1654 THRESHOLD EFFECTS OF WHITE MATTER HYPERINTENSITY VOLUME ON COGNITIVE DECLINE: A 13-YEAR LONGITUDINAL STUDY
Sarvin Sasannia, Shimeng Wang, Keenan Walker, Jerry Prince, Lisa Yanek, Lew Becker, Peter van Zijl, Dhananjay Vaidya, Linda Knutsson, Paul Nyquist · 2026
Read ABSTRACT NUMBER: ESOC2026A1654 THRESHOLD EFFECTS OF WHITE MATTER HYPERINTENSITY VOLUME ON COGNITIVE DECLINE: A 13-YEAR LONGITUDINAL STUDY by Sarvin Sasannia, Shimeng Wang, Keenan Walker, Jerry Prince, Lisa Yanek, Lew Becker, Peter van Zijl, Dhananjay Vaidya, Linda Knutsson, Paul Nyquist (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13145832.txt.
Description
Sarvin Sasannia and co-authors present a 2026 conference study on whether white matter scar growth harms thinking only past a tipping point. These scars in the brain's wiring are common with age and vessel disease. The team tracked scans and tests over thirteen years in a family health group.
More than three hundred adults had scans and thinking tests at the start and again thirteen years later. Below set scar growth levels, hand skill and thinking scores barely moved. Past those levels, hand speed fell steeply and memory screen scores slid faster. Scars near the brain's fluid spaces hurt hand skill more than deep scars did. The authors say total scar load alone hides these cut points.
Catalog record
| CREATOR | Sarvin Sasannia, Shimeng Wang, Keenan Walker, Jerry Prince, Lisa Yanek, Lew Becker, Peter van Zijl, Dhananjay Vaidya, Linda Knutsson, Paul Nyquist |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |