ABSTRACT NUMBER: ESOC2026A1828 SUPER HIGH-FREQUENCY MULTI-OMICS IN ACUTE ISCHEMIC STROKE
Ali Rezaei, Gilamo Atari Kazemi, Lisa Arnold, Apolline Vix, Lars Becker, Andreas Zellner, Chien-Yun Lee, Steffen Tiedt · 2026
Read ABSTRACT NUMBER: ESOC2026A1828 SUPER HIGH-FREQUENCY MULTI-OMICS IN ACUTE ISCHEMIC STROKE by Ali Rezaei, Gilamo Atari Kazemi, Lisa Arnold, Apolline Vix, Lars Becker, Andreas Zellner, Chien-Yun Lee, Steffen Tiedt (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13145650.txt.
Description
Stroke biology shifts hour by hour, but biomarkers are usually sampled daily at best, blurring the sequence. Ali Rezaei and co-authors sampled in 2026 blood every hour for two days from two patients with large-vessel stroke, running proteomics, metabolomics, and peptidomics.
The hourly series revealed ordered, non-monotonic molecular trajectories. One patient, despite similar starting severity, showed rising thromboinflammation and catabolic stress, and fared far worse: a much larger infarct, bleeding into it, and poorer recovery. A molecule called cystathionine rose steadily in that patient, and in a validation cohort of five hundred two it predicted infarct size and worse outcomes. The authors argue hourly sampling unlocks early stratification.
Catalog record
| CREATOR | Ali Rezaei, Gilamo Atari Kazemi, Lisa Arnold, Apolline Vix, Lars Becker, Andreas Zellner, Chien-Yun Lee, Steffen Tiedt |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |