ABSTRACT NUMBER: ESOC2026A2170 TRANSTHYRETIN AS A BIOMARKER FOR POST-STROKE COGNITIVE IMPAIRMENT: INSIGHTS FROM DIMERIZATION AND THYROID HORMONE SIGNALING

Zhiyu Leng, Xiaoyi Jiang, Ming Yuan, Qinxue Sun, Yuhualei Pan, Gang Li · 2026

Read ABSTRACT NUMBER: ESOC2026A2170 TRANSTHYRETIN AS A BIOMARKER FOR POST-STROKE COGNITIVE IMPAIRMENT: INSIGHTS FROM DIMERIZATION AND THYROID HORMONE SIGNALING by Zhiyu Leng, Xiaoyi Jiang, Ming Yuan, Qinxue Sun, Yuhualei Pan, Gang Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13145554.txt.

Description

Zhiyu Leng and five co-authors proposed in 2026 a blood protein as a warning sign for thinking problems after stroke. The protein, transthyretin, carries thyroid hormone and protects the brain, but its shape changes may matter as much as its amount. In mice with stroke plus low oxygen, memory and brain plasticity faltered while the protein shifted form in memory centers.

Injecting its healthy four-part form helped the mice. Blood samples from patients and healthy peers were compared as a first clinical check. If the signal holds, a common blood test could flag patients for early brain care.

Catalog record

CREATORZhiyu Leng, Xiaoyi Jiang, Ming Yuan, Qinxue Sun, Yuhualei Pan, Gang Li
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13145554

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