ABSTRACT NUMBER: ESOC2026YS125 DIMETHYLTRYPTAMINE INHIBITS SPREADING DEPOLARISATION IN BRAIN SLICES OF SIGMA-1 RECEPTORKNOCKOUT MICE
Anna Zsigmond, Rita Frank, Botond Erőss, Andrea Fekete, Ádám Hosszú, Ákos Menyhárt, Sándor Nardai, Eszter Farkas · 2026
Read ABSTRACT NUMBER: ESOC2026YS125 DIMETHYLTRYPTAMINE INHIBITS SPREADING DEPOLARISATION IN BRAIN SLICES OF SIGMA-1 RECEPTORKNOCKOUT MICE by Anna Zsigmond, Rita Frank, Botond Erőss, Andrea Fekete, Ádám Hosszú, Ákos Menyhárt, Sándor Nardai, Eszter Farkas (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13145520.txt.
Description
Anna Zsigmond and co-authors describe a 2026 conference lab study on a compound that may limit a harmful wave of cell stress after stroke. The waves spread through brain tissue and deepen injury. The compound, known as DMT, calms cell harm in animal stroke models, chiefly through one target receptor.
Brain slices from normal mice and mice bred without that receptor were starved of sugar and oxygen to mimic stroke. The compound shrank the tissue zone the waves crossed in both mouse types. In slices lacking the receptor, it also cut wave size and speed. The surprise result points to other receptors doing much of the work, and the team backs more study of the compound.
Catalog record
| CREATOR | Anna Zsigmond, Rita Frank, Botond Erőss, Andrea Fekete, Ádám Hosszú, Ákos Menyhárt, Sándor Nardai, Eszter Farkas |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |