ABSTRACT NUMBER: ESOC2026OT109 EARLY AGGRESSIVE STRATEGY FOR TREATMENT OF LIPID-LOWERING IN ACUTE ISCHEMIC STROKE DELIVERED WITH ENDOVASCULAR THERAPY FOR LARGE ARTERY OCCLUSION (EAST-LDL), PROTOCOL AND UPDATE
Yue Zhang, Chen Chen, Yaping Xiao, Yihai Wang, Zhengyu Huang, Feifeng Liu, Hao Shen, Haiyi Feng, Gang Li · 2026
Read ABSTRACT NUMBER: ESOC2026OT109 EARLY AGGRESSIVE STRATEGY FOR TREATMENT OF LIPID-LOWERING IN ACUTE ISCHEMIC STROKE DELIVERED WITH ENDOVASCULAR THERAPY FOR LARGE ARTERY OCCLUSION (EAST-LDL), PROTOCOL AND UPDATE by Yue Zhang, Chen Chen, Yaping Xiao, Yihai Wang, Zhengyu Huang, Feifeng Liu, Hao Shen, Haiyi Feng, Gang Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13145184.txt.
Description
Yue Zhang and co-authors set out in 2026 the plan for a trial of early, strong fat-lowering after emergency stroke care. Many patients whose blocked brain artery is cleared by catheter still recover poorly, and standard care lacks add-ons against second-wave harm. A PCSK9 blocker can drop blood fats fast and may calm vessel fire. The EAST-LDL trial will enroll 652 patients with front-brain large-artery strokes set for catheter clearing.
Half get one under-skin dose of the blocker before the procedure, on top of standard care; half get standard care alone. The main test is free function at ninety days. Side reads cover nerve recovery, fat drops, fire marks, safety, and quality of life. Assessors stay blind to who got what.
Catalog record
| CREATOR | Yue Zhang, Chen Chen, Yaping Xiao, Yihai Wang, Zhengyu Huang, Feifeng Liu, Hao Shen, Haiyi Feng, Gang Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |