ABSTRACT NUMBER: ESOC2026OT107 RECOMBINANT FACTOR VIIA (RFVIIA) FOR ACUTE HEMORRHAGIC STROKE ADMINISTERED AT EARLIEST TIME (FASTEST) TRIAL
Joseph Broderick, James Grotta, Andrew M Naidech, Jordan Elm, Kazunori Toyoda, Dar Dowlatshahi, Thorsten Steiner, Philip Bath, Carlos Molina, Andrew Demchuk, Heinrich Audebert, J Mocco, Pooja Khatri, Achala Vagal, Lily Wang, Stephan A Mayer, Sohei Yoshimura, Richard Aviv, Emily Stinson, Fastest Inve · 2026
Read ABSTRACT NUMBER: ESOC2026OT107 RECOMBINANT FACTOR VIIA (RFVIIA) FOR ACUTE HEMORRHAGIC STROKE ADMINISTERED AT EARLIEST TIME (FASTEST) TRIAL by Joseph Broderick, James Grotta, Andrew M Naidech, Jordan Elm, Kazunori Toyoda, Dar Dowlatshahi, Thorsten Steiner, Philip Bath, Carlos Molina, Andrew Demchuk, Heinrich Audebert, J Mocco, Pooja Khatri, Achala Vagal, Lily Wang, Stephan A Mayer, Sohei Yoshimura, Richard Aviv, Emily Stinson, Fastest Inve (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13144964.txt.
Description
Joseph Broderick and co-authors lay out the FASTEST trial in a 2026 conference abstract on ultra early treatment for bleeding in the brain. A bleed from a burst vessel grows fast in the first hours, and slowing that growth may save function. The trial tests a clotting drug, recombinant activated factor VII, given within two hours of symptom start in a picked subgroup.
The design is a phase three, multi country, randomized, double blind trial against placebo, with both groups getting best standard care. Early patients had to meet limits on bleed size, alertness, and spread into inner brain spaces. Head scans track bleed growth, and function is scored months later. The abstract notes the first part was stopped, and it stands mainly as a record of the trial design.
Catalog record
| CREATOR | Joseph Broderick, James Grotta, Andrew M Naidech, Jordan Elm, Kazunori Toyoda, Dar Dowlatshahi, Thorsten Steiner, Philip Bath, Carlos Molina, Andrew Demchuk, Heinrich Audebert, J Mocco, Pooja Khatri, Achala Vagal, Lily Wang, Stephan A Mayer, Sohei Yoshimura, Richard Aviv, Emily Stinson, Fastest Inve |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |