ABSTRACT NUMBER: ESOC2026LB19 AN INTERIM ANALYSIS OF THE MULTICENTRIC, RANDOMIZED PHASE 4 CLINICAL TRIAL OF SOVATELTIDE (TYCAMZZI®) IN ACUTE ISCHEMIC STROKE PATIENTS
Anil Gulati, Sikandar Advani, Birinder Paul, Arvind Kankane, Sushma Sharma, U Aruna Kumari, Raghavendra Bs, Pamidimukkala Vijaya, Tushar Patil, Swapnil Samadhiya, Lakshya Jyoti Basumatary, Naveen Korivi, Tcr Ramakrishnan, Thomas Devlin · 2026
Read ABSTRACT NUMBER: ESOC2026LB19 AN INTERIM ANALYSIS OF THE MULTICENTRIC, RANDOMIZED PHASE 4 CLINICAL TRIAL OF SOVATELTIDE (TYCAMZZI®) IN ACUTE ISCHEMIC STROKE PATIENTS by Anil Gulati, Sikandar Advani, Birinder Paul, Arvind Kankane, Sushma Sharma, U Aruna Kumari, Raghavendra Bs, Pamidimukkala Vijaya, Tushar Patil, Swapnil Samadhiya, Lakshya Jyoti Basumatary, Naveen Korivi, Tcr Ramakrishnan, Thomas Devlin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13144928.txt.
Description
Gulati leads a team reporting an interim analysis of a trial of sovateltide in acute ischemic stroke in a 2026 paper. The drug stimulates the endothelin-B receptor and is approved in India for this use. The phase four study is still recruiting there.
Adults with confirmed stroke and at least moderate severity joined within a day of onset. They got the drug or plain saline in three doses over several days. Groups were alike at the start. At ninety days, far more drug-treated patients reached good function scores, and more improved by set margins. A shift analysis also favored the drug. The authors say results match earlier efficacy trials.
Catalog record
| CREATOR | Anil Gulati, Sikandar Advani, Birinder Paul, Arvind Kankane, Sushma Sharma, U Aruna Kumari, Raghavendra Bs, Pamidimukkala Vijaya, Tushar Patil, Swapnil Samadhiya, Lakshya Jyoti Basumatary, Naveen Korivi, Tcr Ramakrishnan, Thomas Devlin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |