Peripheral Blood Regulatory T Cells and IL-6 are Associated with Cognitive Impairment After Acute Ischemic Stroke

Yueyue Chang, Xuke Zhang, Chuanqing Yu, Lei Zhu, Shiyu Sun, Zhongwu Sun · 2026

Read Peripheral Blood Regulatory T Cells and IL-6 are Associated with Cognitive Impairment After Acute Ischemic Stroke by Yueyue Chang, Xuke Zhang, Chuanqing Yu, Lei Zhu, Shiyu Sun, Zhongwu Sun (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13142730.txt.

Description

Yueyue Chang and colleagues measured immune markers after stroke in 2026. Thinking problems often follow an acute ischemic stroke. Two blood factors may help predict that decline. One is a calming immune cell type called regulatory T cells. The other is an inflammatory signal called interleukin six. The team enrolled over two hundred fifty stroke patients. Blood tests measured both factors soon after the event. Cognition was checked again six months later. Patients split into clear, mildly impaired, and dementia groups.

Both markers ran higher in impaired patients. The gap was sharpest for the dementia group. After adjustments, the cell share still predicted impairment. The signal level predicted dementia on its own. Combined, the two markers predicted impairment better than either alone. The authors call both factors risk markers for decline. They also name them as possible treatment targets. The study links immune state to brain recovery after stroke.

Catalog record

CREATORYueyue Chang, Xuke Zhang, Chuanqing Yu, Lei Zhu, Shiyu Sun, Zhongwu Sun
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE55 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13142730

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