Effects of pre- and postnatal probiotic and ω-3 fatty acid supplementation on cytokine and chemokine responses to allergens and TLR ligands during infancy
Cibely C Fontes-Oliveira, Amanda Nylén, Johanna Ljung, Astrid Welin, Lovisa Arvidsson, Magalí Martí, Dhanapal Govindaraj, Isabel García Martín, Camilla Janefjord, Lina Tingö, Ahmed Al-Kaabawi, Elisabet Severin, Karel Duchén, Maria C Jenmalm · 2026
Read Effects of pre- and postnatal probiotic and ω-3 fatty acid supplementation on cytokine and chemokine responses to allergens and TLR ligands during infancy by Cibely C Fontes-Oliveira, Amanda Nylén, Johanna Ljung, Astrid Welin, Lovisa Arvidsson, Magalí Martí, Dhanapal Govindaraj, Isabel García Martín, Camilla Janefjord, Lina Tingö, Ahmed Al-Kaabawi, Elisabet Severin, Karel Duchén, Maria C Jenmalm (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13141264.txt.
Description
Cibely Fontes-Oliveira and co-authors test whether feeding mothers and infants probiotics and fish oil retunes the baby's immune responses. Their 2026 randomized study assigns 117 mother-baby pairs to a probiotic strain, omega-3 fats, both, or placebo, starting mid-pregnancy. Infant blood cells were challenged with allergens and microbial signals across the first two years.
The probiotic clearly shifted response patterns over time; the fish oil showed no clear effect. Probiotic infants produced more of a Th1-linked signal in response to birch and cat allergens at six months, and their immune profiles matured more decisively with age across several stimuli. The authors read this as probiotics promoting immune maturation, a plausible step toward allergy prevention, though clinical allergy outcomes are a longer story. The null result for omega-3 is reported with plainness, which is how supplementation science sorts itself out.
Catalog record
| CREATOR | Cibely C Fontes-Oliveira, Amanda Nylén, Johanna Ljung, Astrid Welin, Lovisa Arvidsson, Magalí Martí, Dhanapal Govindaraj, Isabel García Martín, Camilla Janefjord, Lina Tingö, Ahmed Al-Kaabawi, Elisabet Severin, Karel Duchén, Maria C Jenmalm |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |