Manganese-catalyzed dehydroxyamination of catechols for the synthesis of redox-active and heterocyclic scaffolds
Zahra Naseri Motlagh, Jasem Aboonajmi, Farhad Panahi, Laleh Khalvati, Hashem Sharghi · 2026
Read Manganese-catalyzed dehydroxyamination of catechols for the synthesis of redox-active and heterocyclic scaffolds by Zahra Naseri Motlagh, Jasem Aboonajmi, Farhad Panahi, Laleh Khalvati, Hashem Sharghi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13140292.txt.
Description
Zahra Naseri Motlagh and four co-authors use a manganese salt to swap oxygen for nitrogen in catechols, in this 2026 paper. A catechol is a ring with two hydroxyl groups side by side. Cutting just one bond between carbon and oxygen in such a ring is hard to do cleanly. The products are redox-active building blocks used in drugs and materials.
The salt is manganese nitrate, and it works under mild conditions. With aromatic amines, the method gave 2-(arylamino)phenols in excellent yields. Adding ketones steered the same setup to a set of ring-closed products, the dihydrobenzoxazoles. With aliphatic amines, no halfway product was seen, and benzoxazoles formed at once. The authors report that the method works across a broad range of starting materials, with high selectivity. They present it as a practical route to nitrogen-bearing ring compounds.
Catalog record
| CREATOR | Zahra Naseri Motlagh, Jasem Aboonajmi, Farhad Panahi, Laleh Khalvati, Hashem Sharghi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |