Prospective gait analysis in patients from the French registry of glycogen storage disease type III: implications for clinical trials
Jean-Yves Hogrel, Frédéric Fer, Isabelle Ledoux, François Petit, Martha Darce-Bello, Philippe Labrune, Karim Wahbi, Dalila Habes, Antoine Gardin, Marion Masingue, Pascal Laforêt, Valérie Decostre · 2026
Read Prospective gait analysis in patients from the French registry of glycogen storage disease type III: implications for clinical trials by Jean-Yves Hogrel, Frédéric Fer, Isabelle Ledoux, François Petit, Martha Darce-Bello, Philippe Labrune, Karim Wahbi, Dalila Habes, Antoine Gardin, Marion Masingue, Pascal Laforêt, Valérie Decostre (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13139288.txt.
Description
Glycogen storage disease type III is an inherited disorder that weakens liver and muscle, and many adults with it walk with difficulty. Jean-Yves Hogrel and co-authors measured walking in the French registry for the disease in 2026, following 46 patients aged ten to forty-nine. Each year they timed a six minute walk and recorded trunk motion, leg strength, and motor scores.
Patients walked shorter distances than healthy controls, taking fewer and shorter steps. For most, walking held steady over time, while a broad motor score slipped with age in adults. Low motor scores and some trunk motion traits hinted at who might decline. The authors say the motor score is the best yardstick for future treatment trials.
Catalog record
| CREATOR | Jean-Yves Hogrel, Frédéric Fer, Isabelle Ledoux, François Petit, Martha Darce-Bello, Philippe Labrune, Karim Wahbi, Dalila Habes, Antoine Gardin, Marion Masingue, Pascal Laforêt, Valérie Decostre |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |