Selective alterations in CA1 spine morphology following dietary fructose intake
Mátyás Kapiller, G. Mark Marcello, Diána Hazai, Emese Andrásovszky, Péter Sótonyi, József Szabó, Bence Rácz · 2026
Read Selective alterations in CA1 spine morphology following dietary fructose intake by Mátyás Kapiller, G. Mark Marcello, Diána Hazai, Emese Andrásovszky, Péter Sótonyi, József Szabó, Bence Rácz (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13139255.txt.
Description
Mátyás Kapiller and six co-authors published a 2026 rat study on whether dietary fructose reshapes the tiny spines where brain cells connect. Heavy fructose intake is linked to metabolic and thinking problems, but effects on synapse structure in the hippocampus, a memory hub, were unclear.
Adult rats ate matched diets for four weeks, differing only in whether fructose, glucose, or starch supplied the main carbohydrate. Blood tests showed only modest, diet specific differences, with no major metabolic upset. Under the electron microscope, spine density and most synapse measures matched across groups. Fructose fed rats did show slightly smaller spines with altered roundness. Short term fructose under controlled conditions, the authors conclude, leaves synapses nearly untouched.
Catalog record
| CREATOR | Mátyás Kapiller, G. Mark Marcello, Diána Hazai, Emese Andrásovszky, Péter Sótonyi, József Szabó, Bence Rácz |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |