The role of IP3R and TRPC3 channels in vasoconstriction and hypertension
Raiana dos Anjos Moraes, Quiara Lovatti Alves, Liliane Barreto da Silva, Rafael Leonne Cruz de Jesus, Darízy Flávia Silva · 2026
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Description
Raiana Moraes and co-authors review two calcium channels in blood vessel tightening in 2026. High blood pressure often rests on vessels that stay squeezed too hard. Calcium flow inside vessel muscle cells drives that squeeze. Two channels help control the flow: one frees stored calcium, the other lets calcium enter from outside.
Both channels show raised activity in high blood pressure. The review gathers what studies say about how they work as a pair. Blocking or calming these channels could loosen vessels in a targeted way. The authors frame the pair as leads for new pressure lowering drugs.
Catalog record
| CREATOR | Raiana dos Anjos Moraes, Quiara Lovatti Alves, Liliane Barreto da Silva, Rafael Leonne Cruz de Jesus, Darízy Flávia Silva |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |