Regulation of Cholesterol and Triglyceride Metabolism by Fatty acid Ethanolamides
Sean S Davies, Reza Fadaei · 2026
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Description
Sean Davies and Reza Fadaei review a family of fat-like signal molecules that help set the body's cholesterol and triglyceride levels, in this paper from twenty twenty-six. The molecules, fatty acid ethanolamides, include oleoylethanolamide and palmitoylethanolamide. Body and plant sources both supply them, and supplements of the named two are already sold.
The review gathers new evidence from gene-deletion models and clinical trials. Animals unable to make these molecules handle fats abnormally, while giving the molecules to patients moved lipid levels toward normal. The gut, liver, and fat tissue make them in response to feeding and fasting, and they act through receptors including PPAR-alpha and GPR119. Beyond fats, they help calm inflammation. The authors frame this signaling system as a drug target for fatty liver disease and artery disease.
Catalog record
| CREATOR | Sean S Davies, Reza Fadaei |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |