PARSEbp: pairwise agreement-based RNA scoring with emphasis on base pairings
Sumit Tarafder, Debswapna Bhattacharya · 2026
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Description
Sumit Tarafder and Debswapna Bhattacharya present a 2026 tool for scoring RNA shapes. RNA folds into three-dimensional forms, and picking the best fold from many tries is hard. Tools that score one shape at a time miss the shared pattern across a whole set of tries. That gap hurts ranking and choice of the final model.
Their tool, called PARSEbp, scores shapes by how much they agree with each other. It weighs full shape match plus base pairing match, then builds a shared score table. On contest targets from two recent rounds, the tool beat older scoring methods and deep learning methods. A stripped version without the pairing stress scored worse, showing that part matters.
Catalog record
| CREATOR | Sumit Tarafder, Debswapna Bhattacharya |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |