Rare metachronous isolated splenic metastasis of sigmoid carcinoma: a case report and literature review
Yichao Yan, Xinchun Wu, Junxi Zhu, Yankai Zhang, Lin Chen, Ning Ning · 2026
Read Rare metachronous isolated splenic metastasis of sigmoid carcinoma: a case report and literature review by Yichao Yan, Xinchun Wu, Junxi Zhu, Yankai Zhang, Lin Chen, Ning Ning (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13130060.txt.
Description
Colon cancer almost never spreads to the spleen alone, which makes the organ a diagnostic trap when it does. Yichao Yan and five co-authors report in 2026 a fifty-eight year old man whose sigmoid colon cancer reappeared, years later, as a single splenic deposit and nowhere else. They also review the scattered published cases of the same pattern.
Removing the spleen, then chemotherapy with targeted therapy and an immune drug, kept the man alive with his tumor burden for thirty-two months. Anatomy and immune defenses likely explain the spleen's usual resistance, the authors note. They argue for full combination treatment rather than surgery alone. Watchfulness for new deposits remains part of the plan.
Catalog record
| CREATOR | Yichao Yan, Xinchun Wu, Junxi Zhu, Yankai Zhang, Lin Chen, Ning Ning |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |