CT angiography–derived plaque and perivascular fat radiomics for predicting ipsilateral stroke recurrence in patients with carotid atherosclerosis

Jianyong Wei, Yulu Yang, Xiaoer Wei, Zhiwen Yang, Jingying Tao, Chao Zheng, Shundong Hu, Yueqi Zhu, Yuehua Li · 2026

Read CT angiography–derived plaque and perivascular fat radiomics for predicting ipsilateral stroke recurrence in patients with carotid atherosclerosis by Jianyong Wei, Yulu Yang, Xiaoer Wei, Zhiwen Yang, Jingying Tao, Chao Zheng, Shundong Hu, Yueqi Zhu, Yuehua Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13128431.txt.

Description

Jianyong Wei and eight colleagues mined CT scan textures of carotid plaque and its surrounding fat to predict repeat strokes on the same side. After a first stroke from carotid narrowing, recurrence risk varies widely between patients. The study looked back at patients scanned between 2016 and 2024 and followed them with MRI for recurrence. Software on its own segmented plaque and fat, extracting hundreds of radiomic features.

Three models competed: clinical factors alone, radiomics alone, and both combined, across five learning algorithms. The best was chosen by skill in telling cases apart, and cross-checked again and again. Fat around the artery carries a swelling signal that plain stenosis percentages miss. A model that can be read matters in the clinic, since prevention decisions like surgery need justification. The 2026 work pushes stroke prediction from a single narrowing measurement toward tissue characterization.

Catalog record

CREATORJianyong Wei, Yulu Yang, Xiaoer Wei, Zhiwen Yang, Jingying Tao, Chao Zheng, Shundong Hu, Yueqi Zhu, Yuehua Li
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13128431

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