Case Report: Successful anti-TNF antibody therapy in steroid-dependent segmental colitis associated with diverticulosis and concomitant ulcerative colitis
Fotios Fousekis, Jürgen Siebler, Timo Rath, Arndt Hartmann, Markus F. Neurath, Michael Vieth, Raja Atreya · 2026
Read Case Report: Successful anti-TNF antibody therapy in steroid-dependent segmental colitis associated with diverticulosis and concomitant ulcerative colitis by Fotios Fousekis, Jürgen Siebler, Timo Rath, Arndt Hartmann, Markus F. Neurath, Michael Vieth, Raja Atreya (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13125042.txt.
Description
Two gut diseases that almost never appear together did so in one patient, and a 2026 case report by Fotios Fousekis and co-authors tells how a standard drug calmed both. The rarer disease, segmental colitis tied to diverticulosis, inflames only the bowel stretches that hold the small pouches called diverticula.
The patient was a fifty-six-year-old woman who had part of her colon removed for repeated diverticula trouble. The segmental colitis then flared in the pouches left near the join, alongside left-sided ulcerative colitis. Two gentler drugs healed the colitis but not the segmental disease. An anti-TNF antibody, adalimumab, pushed to a weekly dose, brought full remission of both. Five years on, she stays well without steroids.
Catalog record
| CREATOR | Fotios Fousekis, Jürgen Siebler, Timo Rath, Arndt Hartmann, Markus F. Neurath, Michael Vieth, Raja Atreya |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |