Neuroprotective effects of rutin, sodium selenite, and rutin-conjugated selenium nanoparticles in a social isolation model
Khaled M. Alam-ElDein, Abanoub A. S. Shaker, Manal F. El-Khadragy, Ibrahim K. M. Alabbadi, Ahmed E. Abdel Moneim, Alzahraa A. Elhemiely, Nievin Ahmed Mahran, Triveena M. Ramsis, Shaimaa H. El-Fayoumi, Mohamed A. Ali, Eman Fayad, Haitham Ibrahim El-Mekkawy, Mohamed H. A. Gadelmawla · 2026
Read Neuroprotective effects of rutin, sodium selenite, and rutin-conjugated selenium nanoparticles in a social isolation model by Khaled M. Alam-ElDein, Abanoub A. S. Shaker, Manal F. El-Khadragy, Ibrahim K. M. Alabbadi, Ahmed E. Abdel Moneim, Alzahraa A. Elhemiely, Nievin Ahmed Mahran, Triveena M. Ramsis, Shaimaa H. El-Fayoumi, Mohamed A. Ali, Eman Fayad, Haitham Ibrahim El-Mekkawy, Mohamed H. A. Gadelmawla (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13125023.txt.
Description
A peer-reviewed research article from Europe PMC (2026). BackgroundSocial isolation (SI) is a long-standing experimental paradigm that models schizophrenia-like behavioural and neurobiological changes caused by the action of oxidative stress, neuroinflammation, apoptosis, and neurotransmitter imbalance. The scope of this paper was to comparatively assess the effectiveness of rutin, sodium selenite (Na2SeO3), and rutin-conjugated selenium nanoparticles (RUT-SeNPs) to determine their neuroprotective activity using a rat model of neurobehavioral impairment following SI.MethodsIn silico analysis of Rutin activity including in silico ADMET and toxicity, and molecular docking.
Catalog record
| CREATOR | Khaled M. Alam-ElDein, Abanoub A. S. Shaker, Manal F. El-Khadragy, Ibrahim K. M. Alabbadi, Ahmed E. Abdel Moneim, Alzahraa A. Elhemiely, Nievin Ahmed Mahran, Triveena M. Ramsis, Shaimaa H. El-Fayoumi, Mohamed A. Ali, Eman Fayad, Haitham Ibrahim El-Mekkawy, Mohamed H. A. Gadelmawla |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 87 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |