Mitochondrial dysfunction and oxidative stress in autism spectrum disorder: pharmacological insights into natural antioxidants
Marta Sofia Scenna, Erjola Bej, Patrizia Cesare, Ilaria Persichitti, Annamaria Cimini, Michele D’Angelo, Vanessa Castelli · 2026
Read Mitochondrial dysfunction and oxidative stress in autism spectrum disorder: pharmacological insights into natural antioxidants by Marta Sofia Scenna, Erjola Bej, Patrizia Cesare, Ilaria Persichitti, Annamaria Cimini, Michele D’Angelo, Vanessa Castelli (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13124719.txt.
Description
Marta Sofia Scenna and co-authors review the case for antioxidant therapy in autism spectrum disorder. Autism involves social communication difficulties and fixed, repetitive behavior. Evidence ties it to oxidative stress, faulty mitochondria and brain inflammation. Glutathione stores run low. Damage markers run high. Energy-making machinery in cells underperforms.
The review weighs natural antioxidants one by one. Vitamins E and C, glutathione boosters and plant compounds such as quercetin and curcumin all get scrutiny. So do saffron compounds and indirect helpers like omega-3 fats. Evidence ranges from cell studies to small clinical trials. The authors call the biology real but the therapy unproven, urging careful trials and a broad nutritional approach.
Catalog record
| CREATOR | Marta Sofia Scenna, Erjola Bej, Patrizia Cesare, Ilaria Persichitti, Annamaria Cimini, Michele D’Angelo, Vanessa Castelli |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 93 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |