Pharmacology and toxicology of veterinary isoxazolines: a review
Paulina Markowska-Buńka, Bartosz Rasiński, Hubert Ziółkowski · 2026
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Description
Paulina Markowska-Buńka, Bartosz Rasiński, and Hubert Ziółkowski review a 2026 class of pet drugs that kill fleas and ticks. The drugs, called isoxazolines, have quickly become a mainstay for pets and, more lately, for farm animals. The review covers the four main drugs in the class, from their makeup to their safety.
The drugs block nerve channels in pests, which sparks fatal over-firing, and they bind far more weakly in mammals. Long stay in the body gives lasting cover but raises worry about build-up and late side effects. Trial data show wide safety margins, while reports since launch add notes of care.
Catalog record
| CREATOR | Paulina Markowska-Buńka, Bartosz Rasiński, Hubert Ziółkowski |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |