Peanut Oral Immunotherapy in Children: An Italian Single-Center Retrospective Cohort Study

Benedetta Pessina, Camilla Sertori, Simona Barni, Francesco Catamerò, Giulia Liccioli, Erika Paladini, Lucrezia Sarti, Leonardo Tomei, Julia Upton, Claudia Valleriani, Francesca Mori, Mattia Giovannini · 2026

Read Peanut Oral Immunotherapy in Children: An Italian Single-Center Retrospective Cohort Study by Benedetta Pessina, Camilla Sertori, Simona Barni, Francesco Catamerò, Giulia Liccioli, Erika Paladini, Lucrezia Sarti, Leonardo Tomei, Julia Upton, Claudia Valleriani, Francesca Mori, Mattia Giovannini (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13118600.txt.

Description

Benedetta Pessina and co-authors review peanut immunotherapy in children at one Italian center, in a study published in 2026. The therapy feeds tiny, growing doses of peanut to retrain the immune system. A standard drug product exists abroad but is not available everywhere, so this center used toasted peanuts in a home-grown protocol.

They followed sixty children who started treatment between 2015 and 2024, with a median age of about eight. About a third reached the target dose, tolerating a full serving's worth of peanut protein, after roughly twenty-three months. A third were still in progress, and the rest had stopped, most often by dropping out. Reactions occurred in most children but were mostly mild and settled on their own. The authors call the approach feasible with careful supervision.

Catalog record

CREATORBenedetta Pessina, Camilla Sertori, Simona Barni, Francesco Catamerò, Giulia Liccioli, Erika Paladini, Lucrezia Sarti, Leonardo Tomei, Julia Upton, Claudia Valleriani, Francesca Mori, Mattia Giovannini
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13118600

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