Multiscale Comparative Analyses of OVB-Organoids and Cerebral Organoids
Jingyi Yang, Xue Zhang, Shuang Li, Zhixian Gao · 2026
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Description
Jingyi Yang and three co-authors compare two kinds of lab-grown brain tissue to see which better copies early human development. Their study appeared in twenty twenty-six. Tiny organ-like balls of cells, called organoids, let scientists watch the brain form, but single types cannot show how organs interact.
One model grows the brain alone. The other also grows the optic vesicle, the early eye bud, alongside it. Using stains and gene activity maps, the team found clear gaps between the two. The combined model formed eye-like structures and switched on a marker gene tied to the retina. Its gene patterns matched real early development more closely. The authors offer it as a stronger base for studying eye and brain growth together.
Catalog record
| CREATOR | Jingyi Yang, Xue Zhang, Shuang Li, Zhixian Gao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |