Epigenetic Biomarkers for Predicting Nucleoside Analog Drug Response and Resistance in Cancer
John Kaszycki, Jackson C. Lin, Minji Kim, Hunmin Jung · 2026
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Description
A peer-reviewed research article from Europe PMC (2026). Nucleoside analogs (NAs) play a central role in cancer therapy, either through direct cytotoxicity or epigenome reprogramming. They are clinically effective but have shortcomings in their long-term effectiveness because of variable patient responses and the emergence of resistance. There is growing evidence that DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs (ncRNAs) are key factors that determine sensitivity and resistance to NAs.
Catalog record
| CREATOR | John Kaszycki, Jackson C. Lin, Minji Kim, Hunmin Jung |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |