Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells
Irmak Fatoş Korkmaz, Tugba Elgun, Çiğdem Aktas, Ersin Gündeğer, Asiye Gok Yurttas · 2026
Read Ketamine Induces Apoptosis and Inhibits Proliferation in HT-29 Colorectal Cancer Cells by Irmak Fatoş Korkmaz, Tugba Elgun, Çiğdem Aktas, Ersin Gündeğer, Asiye Gok Yurttas (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13113080.txt.
Description
Irmak Fatoş Korkmaz and four co-authors test whether the anesthetic ketamine can also kill colon cancer cells in a dish. Colorectal cancer is common and deadly, and recent work hints that anesthetics touch cancer cell survival directly. Their 2026 study treats HT-29, a human colorectal cancer cell line, with ketamine for twenty-four hours. A standard viability test measures how many cells live, and flow cytometry counts those entering programmed death.
The title states the outcome: ketamine drove death and slowed growth in these cells. Lab-dish results are a long way from patient benefit, but they flag drugs worth a second look. Anesthetics are given during cancer surgery anyway, so any anti-cancer side effect would be free. The authors frame the work as an early in vitro probe. It joins a wider rethink of what surgical drugs do beyond sleep.
Catalog record
| CREATOR | Irmak Fatoş Korkmaz, Tugba Elgun, Çiğdem Aktas, Ersin Gündeğer, Asiye Gok Yurttas |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |