Mycobacterium tuberculosis infection disrupts gut and respiratory microbial communities and networks with incomplete restoration after two months of treatment
Sohyoung Won, Juyong Hong, Heebal Kim, Junho Lee, Young Chun Ko, Bumhee Yang, Sun-Hyung Kim, Seok Shin Koh, Jeeyeon Park, Gee Oh Guak, Gyeong In Lee, Youngeun Choi, Seung Heon Lee, Gisu Kang, Seoae Cho, Hyejin Kim · 2026
Read Mycobacterium tuberculosis infection disrupts gut and respiratory microbial communities and networks with incomplete restoration after two months of treatment by Sohyoung Won, Juyong Hong, Heebal Kim, Junho Lee, Young Chun Ko, Bumhee Yang, Sun-Hyung Kim, Seok Shin Koh, Jeeyeon Park, Gee Oh Guak, Gyeong In Lee, Youngeun Choi, Seung Heon Lee, Gisu Kang, Seoae Cho, Hyejin Kim (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13107742.txt.
Description
Sohyoung Won and a large team of co-authors report, in a 2026 study, how tuberculosis reshapes the microbes of the gut and airways. The lungs and gut trade signals, a link called the gut-lung axis, but how TB and its treatment move that link was unclear. The team took paired stool and airway samples from patients at diagnosis and after two months of treatment, plus matched healthy controls.
Infection shifted the mix of species in both sites and rewired their networks. Patients had fewer species that make short-chain fatty acids, which calm swelling, and more species tied to inflammation. After two months of treatment the networks had only partly healed. Species that held central spots differed by group, which names candidates for later study.
Catalog record
| CREATOR | Sohyoung Won, Juyong Hong, Heebal Kim, Junho Lee, Young Chun Ko, Bumhee Yang, Sun-Hyung Kim, Seok Shin Koh, Jeeyeon Park, Gee Oh Guak, Gyeong In Lee, Youngeun Choi, Seung Heon Lee, Gisu Kang, Seoae Cho, Hyejin Kim |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |