Letter to the Editor: Commentary on “Prognostic significance of the albumin-to-alkaline phosphatase ratio in gastrointestinal cancer patients: a systematic review and meta-analysis”
Yiwen Wang, Peihong Li, Yikun Zhang · 2026
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Description
Yiwen Wang, Peihong Li, and Yikun Zhang wrote a 2026 letter on a blood ratio used to predict outcomes in gut cancers. The ratio, called AAPR, divides albumin by alkaline phosphatase, two values from a standard blood test. A pooled review had found that the ratio may forecast how patients with these cancers will fare.
The letter praises the review, then adds cautions. Cancers of the stomach, colon, pancreas, and liver differ a lot in how they grow and spread. Both parts of the ratio shift with tumor load, liver strain, and blocked bile flow. Pooling all gut cancers at once may hide those contrasts. The authors urge tests of the ratio in each cancer type on its own, so doctors know where it truly helps.
Catalog record
| CREATOR | Yiwen Wang, Peihong Li, Yikun Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 4 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |