The Central Role of Lipid Metabolism Disorders in Diabetes Mellitus: Mechanisms, Clinical Manifestations, and Emerging Therapeutic Strategies
Qiang Yang, Xueting Liu, Tianyi Zhang, Xu Zhao, Xiaohe Xiao · 2026
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Description
Yang and co-authors review in 2026 the central role of fat handling faults in diabetes. Diabetes pairs high blood sugar with disordered fats, and the fat side is not a mere rise in levels. Whole lipoprotein systems and pathways fall out of step, which drives and speeds the disease.
Fat faults worsen sugar harm to heart and brain vessels and harm small vessels in kidney and eye through fat toxicity. Paths span insulin resistance, sugar driven fat making, cell stress, and hormone imbalance. The review covers signs, clinical features, and care plans. It gives weight to new drugs that target gut germs or swelling as future options.
Catalog record
| CREATOR | Qiang Yang, Xueting Liu, Tianyi Zhang, Xu Zhao, Xiaohe Xiao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |