A novel photosensitizer-based photodynamic therapy reprograms the Kynurenine–AhR axis to boost antitumor immunity in breast cancer
Yuetong Liu, Ge Hong, Tianjun Liu, Hong Liu · 2026
Read A novel photosensitizer-based photodynamic therapy reprograms the Kynurenine–AhR axis to boost antitumor immunity in breast cancer by Yuetong Liu, Ge Hong, Tianjun Liu, Hong Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13094649.txt.
Description
Yuetong Liu, Ge Hong, Tianjun Liu, and Hong Liu test a light-based therapy that wakes up the immune system against breast cancer, in a study from 2026. The therapy uses a light-sensitive drug that kills tumor cells when lit. Its immune effects were less clear. Their new drug, called DTP, gathers in tumors and fires harsh oxygen chemicals under red light.
Treated tumors shrank and showed fewer dividing cells. A chemical scan found the therapy cut levels of a compound that mutes immune attack. With that brake eased, killer T cells poured in and calming T cells fell. Adding a standard immune drug boosted the effect and curbed lung spread. Memory immune cells also grew, which hints at lasting guard. The authors frame the therapy as both a local strike and an immune primer.
Catalog record
| CREATOR | Yuetong Liu, Ge Hong, Tianjun Liu, Hong Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |