Decoding the Causal Effects of Blood-Related Phenotypes in Hypertrophic Scars and Keloids: A Mendelian Randomization Study
Fang Zhou, Gao Zeng · 2026
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Description
A peer-reviewed research article from Europe PMC (2026). BackgroundHypertrophic scars (HS) and keloids are pathological outcomes of aberrant wound healing. Their association with systemic physiological factors remains unclear. Mendelian randomization (MR) uses genetic variants as instrumental variables (IVs) to infer causality, minimizing confounding factors.ObjectiveIn this study, we aim to investigate the causal effects of blood-related phenotypes, including blood cell counts, blood pressure, lipids, and glucose, on the risk of HS and keloids using a two-sample MR method.MethodsGenetic instruments for exposures were obtained from publicly available GWAS summary statistics, while outcome
Catalog record
| CREATOR | Fang Zhou, Gao Zeng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |