A Herbal Pair of Taraxacum officinale F.H.Wigg. and Lonicera japonica Thunb. Ameliorates Obesity and Modulates AMPK Signaling
Seong Chul Jin, You Yeon Choi, Batsukh Sosoburam, Hee Kyung Baek, Min Woo Song, Seungyob Yi, Ji Eun Park, Woong Mo Yang · 2026
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Description
Seong Chul Jin and seven co-authors test a two-herb formula against obesity in cells and mice, in this 2026 study. LIPO-700 blends honeysuckle and dandelion, a traditional pairing now standardized. Computer analysis of its predicted targets pointed first at AMPK, the cell's fuel gauge, among the enriched pathways.
In fat cells grown in dishes, the formula cut lipid accumulation by up to 19 percent; in fatty liver cells, by about 25 percent. AMPK activation rose three and a half fold, fat-burning enzymes were restored, and fat-building ones suppressed. Obese mice fed a high-fat diet then received the formula by mouth. Weight, fat mass, and fat cell size all fell in step with dose, and neither liver nor kidney showed toxicity. Tissue analysis confirmed the same AMPK-centered signature seen in the dishes. The authors present a coherent mechanism, from molecule to mouse.
Catalog record
| CREATOR | Seong Chul Jin, You Yeon Choi, Batsukh Sosoburam, Hee Kyung Baek, Min Woo Song, Seungyob Yi, Ji Eun Park, Woong Mo Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |