Multitissue, multi–time point transcriptomic atlas of aging in mice and rats

Tea Shavlakadze, Kun Xiong, Romain Donne, Corissa McEwen, Abhilash Gadi, Matthew Wakai, Hunter Salmon, Jacob Treinish, Elias Pavlopoulos, Larry Proctor, Shuo Li, Nicole Negron, Min Ni, Yi Wei, Yu Bai, David J. Glass · 2026

Read Multitissue, multi–time point transcriptomic atlas of aging in mice and rats by Tea Shavlakadze, Kun Xiong, Romain Donne, Corissa McEwen, Abhilash Gadi, Matthew Wakai, Hunter Salmon, Jacob Treinish, Elias Pavlopoulos, Larry Proctor, Shuo Li, Nicole Negron, Min Ni, Yi Wei, Yu Bai, David J. Glass (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13082319.txt.

Description

To determine the genes and pathways that are up- or down-regulated in a consistent manner throughout the rodent lifespan, we generated a high N age-related gene expression atlas in mice and rats, by profiling 28 tissues in male and female C57BL/6J mice and 32 tissues in male Sprague Dawley rats (>5000 samples) over multiple time points.

Catalog record

CREATORTea Shavlakadze, Kun Xiong, Romain Donne, Corissa McEwen, Abhilash Gadi, Matthew Wakai, Hunter Salmon, Jacob Treinish, Elias Pavlopoulos, Larry Proctor, Shuo Li, Nicole Negron, Min Ni, Yi Wei, Yu Bai, David J. Glass
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE78 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13082319

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