Prenatal exposure to buprenorphine or methadone and adverse neurodevelopmental outcomes: population based cohort study

Sabine Friedrich, Krista F Huybrechts, Loreen Straub, Sonia Hernandez-Diaz, Yanmin Zhu, Georg Hahn, Helen Mogun, Hendrée E Jones, Hilary S Connery, Jonathan M Davis, Kathryn J Gray, Barry Lester, Mishka Terplan, Brian T Bateman · 2026

Read Prenatal exposure to buprenorphine or methadone and adverse neurodevelopmental outcomes: population based cohort study by Sabine Friedrich, Krista F Huybrechts, Loreen Straub, Sonia Hernandez-Diaz, Yanmin Zhu, Georg Hahn, Helen Mogun, Hendrée E Jones, Hilary S Connery, Jonathan M Davis, Kathryn J Gray, Barry Lester, Mishka Terplan, Brian T Bateman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13081224.txt.

Description

ObjectiveTo compare the incidence of neurodevelopmental disorders among children with prenatal exposure to buprenorphine versus methadone.DesignPopulation based cohort study.SettingUS nationwide Medicaid data on >2.5 million live births from 2000 to 2018.Participants18 612 pregnancies exposed to buprenorphine or methadone, of which 587 were excluded from the analysis owing to exposure to the comparator drug.

Catalog record

CREATORSabine Friedrich, Krista F Huybrechts, Loreen Straub, Sonia Hernandez-Diaz, Yanmin Zhu, Georg Hahn, Helen Mogun, Hendrée E Jones, Hilary S Connery, Jonathan M Davis, Kathryn J Gray, Barry Lester, Mishka Terplan, Brian T Bateman
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13081224

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