Exosome–niosome hybrid oxygen carrier for protection against acetaminophen-induced acute liver injury
Anika Bushra, Dalton Jayne, Thomas Locke, Xiaoxue Han, Timothy M. Fan, Gregory H. Underhill, Joseph Irudayaraj · 2026
Read Exosome–niosome hybrid oxygen carrier for protection against acetaminophen-induced acute liver injury by Anika Bushra, Dalton Jayne, Thomas Locke, Xiaoxue Han, Timothy M. Fan, Gregory H. Underhill, Joseph Irudayaraj (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13037704.txt.
Description
Anika Bushra and co-authors build a hybrid oxygen carrier to protect the liver from damage by a common pain drug, in a paper from 2026. Overdose of acetaminophen is a major cause of sudden liver injury. Low oxygen, oxidant stress, and inflammation drive the harm.
Their carrier joins cell-derived parcels, taken from blueberries, with synthetic bubbles called niosomes. The system holds oxygen and releases it slowly for many hours, even in low-oxygen conditions. Its size and charge were measured, and it kept for months in cold storage. In liver cell tests under low oxygen, it cut damage from oxidants and from the drug, including in three-dimensional cell clusters treated a day after injury. Safety tests supported further study.
Catalog record
| CREATOR | Anika Bushra, Dalton Jayne, Thomas Locke, Xiaoxue Han, Timothy M. Fan, Gregory H. Underhill, Joseph Irudayaraj |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |