Role of Galectin-1 in the Pathogenesis of Melanoma
Grace Kim, Thea Blackwell, Kimiya Banai, Rowen Lin, Justin Chung, Devendra K. Agrawal · 2025
Read Role of Galectin-1 in the Pathogenesis of Melanoma by Grace Kim, Thea Blackwell, Kimiya Banai, Rowen Lin, Justin Chung, Devendra K. Agrawal (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13035363.txt.
Description
Grace Kim, Thea Blackwell, Kimiya Banai, Rowen Lin, Justin Chung, and Devendra Agrawal review how a sugar-binding protein helps melanoma grow and dodge care. Their 2025 review covers galectin-1, a protein that steers immune cells, blood vessel growth, and cell spread in many tissues.
Inside tumors, the protein calms immune attack and helps cancer build new vessels and seed new sites. In melanoma it also blunts response to key drugs and to chemo, and feeds cell shape shifting. Drug blockers and imaging tracers that target the protein are in development. Wide roles elsewhere in the body, from heart protection to nerve repair, limit safe targeting. The authors call for ways to confine blockers to cancer cells.
Catalog record
| CREATOR | Grace Kim, Thea Blackwell, Kimiya Banai, Rowen Lin, Justin Chung, Devendra K. Agrawal |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |