Progestins - a review of clinical application in gynecology

Dominika Żyła, Dominika Kuźmiuk, Martyna Rynkowska, Małgorzata Satora, Krzysztof Kułak, Rafał Tarkowski · 2025

Read Progestins - a review of clinical application in gynecology by Dominika Żyła, Dominika Kuźmiuk, Martyna Rynkowska, Małgorzata Satora, Krzysztof Kułak, Rafał Tarkowski (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12985400.txt.

Description

Dominika Zyla and colleagues review how progestins, a family of hormone-like drugs related to progesterone, are used in gynecology and beyond. The family sorts into three chemical classes and four generations by origin. Writing in twenty twenty-five, the team searched major databases for clinical studies and trials from the past two decades. Uses in women and men were both covered, whether the drugs are given alone or combined with estrogen.

Contraception is the primary use, in pill, implant, and other forms. The same drugs also treat heavy or irregular bleeding, endometriosis, absent periods, infertility, and overgrowth of the womb lining. Balanced against estrogen, they protect the womb lining from cancer. They ease menopause symptoms in hormone therapy and can help prevent early delivery. The authors note active trials and warn that off-label use needs care.

Catalog record

CREATORDominika Żyła, Dominika Kuźmiuk, Martyna Rynkowska, Małgorzata Satora, Krzysztof Kułak, Rafał Tarkowski
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE69 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12985400

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